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CoenzymesofOxidationReductionReactions O HN N HN H2N N N R NADPH DHF Serine Glycine 2-Oxovalerate O H COO R CC N COO H or polyglutamates Methionine Methane a R NADPH O Scalpint Folate b HH N or Forfx C HN H2N N N H Tetrahydrofolate O cc H CO2 (nonenzymatic) Gly NADPH HN 6 i HN R NN R Homocysteine 2-Oxopantoate O H2C N H O CH3 HN NADP H2NNN jDHFH2NNN HH Purines Formimino-Gly Histidine Formimino-Glu 5,10-Methylene-THF NADP d k 5-Methyl-THF Thymine (thymidylate) Hydroxymethylcytosine (hydroxymethyldeoxy CMP) HN O CH HN R NADPH O HC N O HC HN R RO N NH3 N OHm N5 HNhHN HN l H2N N N H2N N N ADPATPH2N N N H H Pi H 5-Formimino-THF 5,10-Methenyl-THF H2O e 10 ONR 5-Formyl-THF (leucovorin) Purines Formylmethionine O HC H2O g O n O HC Formate g ATP HN H N5 N N H 10-Formyl-THF o f NADPH p CO2 CO ADP Pi H2N NADP Figure 15-18 Tetrahydrofolic acid and its one-carbon derivatives.
4 PROPAGATION OF BEAMS IN NONLINEAR MEDIA 399 Figure 12. Lanham, however, more reactive and cyclize more readily than the chlorides.xi, xvii Warner, J. Experimentaltra- cheal homografting.
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